First introduced as a midseason replacement in 2005, ABC's medical drama Grey's Anatomy became an instant success. Over the years, fans have shared their favorite Grey's Anatomy quotes as a way to show appreciation for, and a connection to, the show's surgical interns, residents, and attending physicians.
You can build a house out of anything, make it as strong as you want. But a home, a home is more fragile than that. A home is made of the people you fill it with.
Played by Ellen Pompeo on ABC's "Grey's Anatomy" (Season 11, Episode 25)
Do not alarm the makers of the tiny humans. They will eat you alive.Arizona Robbins
Dr. Yang and my wife sometimes have sleepovers in my bed. With me in it.Derek Shepherd
If you knew this was your last day on earth, how would you want to spend it?Meredith Grey
It's good to be scared. It means you still have something to lose.Richer Webber
It's like candy, but with blood, which is so much better.Christina Yang
We're adults. When did that happen? And how do we make it stop?Meredith Grey
It's a beautiful day to save lives. Let's have some fun.Derek Shepherd
Maybe we're not supposed to be happy. Maybe gratitude has nothing to do with joy. Maybe being grateful means recognizing what you have for what it is. Appreciating small victories. Admiring the struggle it takes to simply be human. Maybe, we're thankful for the familiar things we know. And maybe we're thankful for the things we'll never know. At the end of the day, the fact that we have the courage to still be standing is reason enough to celebrate.Meredith Grey
Damn it. I'm a bad sponge. A leaky sponge. I'm gonna leak all the wrong secrets. I'm a bad liar. I can't even lie about talking to myself.George O'Malley
I know it's not perfect, but it's life. Life is messy sometimes.Edward Levangie
What self-respecting surgeon wears salmon colored scrubs?Isobel "Izzie" Stevens
Katie: My head's all full. Meredith: That's called thinking. Go with it.Grey, Meredith and Bryce, Katie
Have some fire. Be unstoppable. Be a force of nature. Be better than anyone here, and don't give a damn what anyone thinks.Christina Yang
If you love someone, you tell them. Even if you're scared that it's not the right thing. Even if you're scared that it'll cause problems. Even if you're scared that it'll burn your life to the ground, you say it.Mark Sloan
What's broken can be mended, what's hurt can be healed. No matter how dark it gets, the sun's gonna rise again.Meredith Grey
Time flies. Time waits for no man. Time heals all wounds. All any of us wants is more time. Time to stand up. Time to grow up. Time to let go. Time...Meredith Grey
Screw beautiful. I'm brilliant! If you want to appease me, compliment my brain.Christina Yang
Turns out, sometimes you have to do the wrong thing. Sometimes you have to make big mistake to figure out how to make things right. Mistakes are painful, but they're the only way to find out who you really are.Denny Duquette
Just when we think we figured things out, the universe throws us a curveball.Meredith Grey
Grey's Anatomy originally revolved around the life of Dr. Meredith Grey, a new intern who fell in love with attending physician Dr. Derek Shepherd. Over the years, fans saw her struggle to advance in her career while juggling the demands of friendships, romance, and parenthood. Many of the show’s best quotes come from Dr. Grey's conversations with her close friends Dr. Christina Yang and Dr. Alex Karev as they faced these challenges together.
Part of Grey's Anatomy's continued success can be attributed to the fact that the show evolved over the years to introduce multiple characters with complex backstories. By its twelfth season, sixteen actors had top billing—including just four from the original cast. This diversity gave fans an endless source of new Grey's Anatomy quotations to share, showcasing a wider range of perspectives than what was seen in the earlier seasons. The show's main characters included military veterans, single parents, evangelical Christians, former foster children, and privileged Ivy League graduates—all of whom found ways to share common ground despite their differences.
Although much of Grey's Anatomy centers around the complex medical needs of patients at the hospital, it's the human connection between characters that most appeals to diehard fans. We can't all be surgeons, but there's a universal appeal to the idea of making a difference while trying to find your own path in life.