More often than not, nothingness is reluctantly and despairingly taken to be the only hypothesis possible when all the others have failed, since by definition it cannot be disproven and is beyond the scope of reason.
Headmaster: Clad in the magnificent white silk robes of an Arab prince, with in his belt the short curved, gold sword of the Ashraf descendants of the Prophet, he hoped to pass unnoticed through London. Alas, he was mistaken. "Who am I?" he would cry despairingly. "You are Lawrence of Arabia" passers-by would stop him and say, "And I claim my five pounds."Alan Bennett
I despaired of the possibility of discovering the true laws by means of constructive efforts based on known facts. The longer and the more despairingly I tried, the more I came to the conviction that only the discovery of a universal formal principle could lead us to assured results.