Elaine? Do me a favor... [LeChuck: Arrr, THAT be the stuff... Elaine: Anything...] Kick his two-faced butt for me...
Who: Guybrush Threepwood
Source: Tales of Monkey Island Chapter 4: The Trial and Execution of Guybrush Threepwood
Notes: Main character is mortally wounded by a stab in the chest from the Cutlass of Kaflu inflicted by LeChuck after having cured Elaine and everyone else from the deadly pox. As said protagonist is dying, he tells her to stop LeChuck for him, to which she imparts her tearful words, "From Mêlée to Monkey and all the islands in between, my love," and after she imparts her tearful kiss, he takes one final empty gaze at her before he dies, right after LeChuck regains his undead form from the voodoo-absorbent Esponja Grande. Like Morgan LeFlay, Guybrush reappears as a ghost in the Crossroads and eventually returns to life in the game's final chapter, Rise of the Pirate God.